Drug Test Kit TCA Rapid Diagnostic Test strip, Gold colloidal
method, detecting Nortriptyline in urine, 1000ng/ml
One Step TCA Rapid Diagnostic Test Strip
|Product||Cat No||Specimen||Sensitivity||Format||Kit Size|
|TCA||YD151S3||Urine||1000 ng/mL||3mm Strip||100T|
The TCA Rapid Test Strip (Urine) is a lateral flow chromatographic
immunoassay for the detection of Nortriptyline in human urine at a
cut-off concentration of 1,000 ng/mL. This test will detect other
related compounds, please refer to the Analytical Specificity table
in this package insert. This assay provides only a preliminary
analytical test result. A more specific alternate chemical method
must be used in order to obtain a confirmed analytical result. Gas
chromatography/mass spectrometry (GC/MS) or high performance liquid
chromatography (HPLC) are the preferred confirmatory methods.
Clinical consideration and professional judgment should be applied
to any drug of abuse test result, particularly when preliminary
positive results are used.
TCA (Tricyclic Antidepressants) are commonly used for the treatment
of depressive disorders. TCA overdoses can result in profound
central nervous system depression, cardiotoxicity and
anticholinergic effects. TCA overdose is the most common cause of
death from prescription drugs. TCAs are taken orally and sometimes
by injection. TCAs are metabolized in the liver, both TCAs and
their metabolites are excreted in urine mostly in the form of
metabolites for up to ten days. The TCA Rapid Test Dipstick (Urine)
is a rapid urine-screening test that can be performed without the
use of an instrument. The test utilizes a monoclonal antibody to
selectively detect elevated levels of nortriptyline in urine. The
TCA Rapid Test Dipstick (Urine) yields a positive result when the
Nortriptyline in urine exceeds 1,000 ng/mL.
DIRECTIONS FOR USE
- Bring the pouch to room temperature before opening it. Remove the
Test Dipstick from the sealed pouch and use it within one hour.
- With arrows pointing towards the urine specimen, immerse the Test
Dipstick vertically in the urine specimen in such a way that urine
does not cross MAX line on the Test Dipstick for 10-15 seconds. See
the illustration below.
- Wait for the color line(s) to appear. The result should be read at
5 minutes. Do not interpret the result after 10 minutes.
INTERPRETATION OF RESULTS
NEGATIVE:* A colored line appears in the Control region (C) and colored lines
appears in the Test region (T). This negative result means that the
concentrations in the urine sample are below the designated cut-off
levels for a particular drug tested.
*NOTE: The shade of the colored lines(s) in the Test region (T) may
vary. The result should be considered negative whenever there is
even a faint line.
POSITIVE: A colored line appears in the Control region (C) and NO line
appears in the Test region (T). The positive result means that the
drug concentration in the urine sample is greater than the
designated cut-off for a specific drug.
INVALID: No line appears in the Control region (C). Insufficient specimen
volume or incorrect procedural techniques are the most likely
reasons for Control line failure. Read the directions again and
repeat the test with a new test card. If the result is still
invalid, contact your manufacturer.
- The TCA Rapid Test Dipstick (Urine) provides only a preliminary
analytical result. A secondary analytical method must be used to
obtain a confirmed result. Gas chromatography/mass spectrometry
(GC/MS) or high performance liquid chromatography (HPLC) are the
preferred confirmatory methods.
- The TCA Rapid Test Dipstick (Urine) is a qualitative screening
assay and can not determine either the drug concentration in the
urine or the level of intoxication.
- It is possible that technical or procedural errors, as well as
other interfering substances in the urine specimen may cause
- Adulterants, such as bleach and/or alum, in urine specimens may
produce erroneous results regardless of the analytical method used.
If adulteration is suspected, the test should be repeated with
another urine specimen.
- A positive result indicates presence of the drug or its metabolites
but does not indicate level or intoxication, administration route
or concentration in urine.
- A negative result may not necessarily indicate drug-free urine.
Negative results can be obtained when drug is present but below the
cut-off level of the test.
A comparison was conducted using the TCA Rapid Test Dipstick
(Urine) and GC/MS. The following results were tabulated:
|TCA Rapid Test||Results||Positive||Negative||Results|